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spr analysis cm5 sensor chip  (Biacore)

 
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    Biacore spr analysis cm5 sensor chip
    Spr Analysis Cm5 Sensor Chip, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spr analysis cm5 sensor chip/product/Biacore
    Average 86 stars, based on 1 article reviews
    spr analysis cm5 sensor chip - by Bioz Stars, 2026-06
    86/100 stars

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    spr analysis  (GE Healthcare)
    96
    GE Healthcare spr analysis
    Inhibitor 19 is a potent and selective SCoV2 PLpro inhibitor (A) Chemical structures of 12 and 19 . (B and C) Inhibitor 19 was docked into the binding pocket of 12 in SCoV2 PLpro (chain A, PDB: 7E35 ). Superimposition of 19 (purple sticks) and 12 (azure sticks) indicated additional interactions between 19 and Tyr269-Gln 270 (green sticks in B) of SCoV2 PLpro (surface in C). (D) <t>SPR</t> <t>analysis</t> of 19 binding to SCoV2 PLpro; GRL0617 was used as a control. K d and SD were calculated based on three independent experiments. (E) A bar graph showing the inhibition of 11 DUBs or DUB-like proteases by 19 (10 μM) (n = 3). Data are presented as the mean ± SD (n = 3).
    Spr Analysis, supplied by GE Healthcare, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spr analysis/product/GE Healthcare
    Average 96 stars, based on 1 article reviews
    spr analysis - by Bioz Stars, 2026-06
    96/100 stars
    		  Buy from Supplier
    spr analysis cm5 sensor chip  (Biacore)
    86
    Biacore spr analysis cm5 sensor chip
    Inhibitor 19 is a potent and selective SCoV2 PLpro inhibitor (A) Chemical structures of 12 and 19 . (B and C) Inhibitor 19 was docked into the binding pocket of 12 in SCoV2 PLpro (chain A, PDB: 7E35 ). Superimposition of 19 (purple sticks) and 12 (azure sticks) indicated additional interactions between 19 and Tyr269-Gln 270 (green sticks in B) of SCoV2 PLpro (surface in C). (D) <t>SPR</t> <t>analysis</t> of 19 binding to SCoV2 PLpro; GRL0617 was used as a control. K d and SD were calculated based on three independent experiments. (E) A bar graph showing the inhibition of 11 DUBs or DUB-like proteases by 19 (10 μM) (n = 3). Data are presented as the mean ± SD (n = 3).
    Spr Analysis Cm5 Sensor Chip, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spr analysis cm5 sensor chip/product/Biacore
    Average 86 stars, based on 1 article reviews
    spr analysis cm5 sensor chip - by Bioz Stars, 2026-06
    86/100 stars
    		  Buy from Supplier

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    Inhibitor 19 is a potent and selective SCoV2 PLpro inhibitor (A) Chemical structures of 12 and 19 . (B and C) Inhibitor 19 was docked into the binding pocket of 12 in SCoV2 PLpro (chain A, PDB: 7E35 ). Superimposition of 19 (purple sticks) and 12 (azure sticks) indicated additional interactions between 19 and Tyr269-Gln 270 (green sticks in B) of SCoV2 PLpro (surface in C). (D) SPR analysis of 19 binding to SCoV2 PLpro; GRL0617 was used as a control. K d and SD were calculated based on three independent experiments. (E) A bar graph showing the inhibition of 11 DUBs or DUB-like proteases by 19 (10 μM) (n = 3). Data are presented as the mean ± SD (n = 3).

    Journal: Cell Chemical Biology

    Article Title: Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2

    doi: 10.1016/j.chembiol.2021.04.020

    Figure Lengend Snippet: Inhibitor 19 is a potent and selective SCoV2 PLpro inhibitor (A) Chemical structures of 12 and 19 . (B and C) Inhibitor 19 was docked into the binding pocket of 12 in SCoV2 PLpro (chain A, PDB: 7E35 ). Superimposition of 19 (purple sticks) and 12 (azure sticks) indicated additional interactions between 19 and Tyr269-Gln 270 (green sticks in B) of SCoV2 PLpro (surface in C). (D) SPR analysis of 19 binding to SCoV2 PLpro; GRL0617 was used as a control. K d and SD were calculated based on three independent experiments. (E) A bar graph showing the inhibition of 11 DUBs or DUB-like proteases by 19 (10 μM) (n = 3). Data are presented as the mean ± SD (n = 3).

    Article Snippet: SPR analysis , GE Healthcare , Cat# BR-1005-30.

    Techniques: Binding Assay, Inhibition

    Journal: Cell Chemical Biology

    Article Title: Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2

    doi: 10.1016/j.chembiol.2021.04.020

    Figure Lengend Snippet:

    Article Snippet: SPR analysis , GE Healthcare , Cat# BR-1005-30.

    Techniques: Produced, Recombinant, Activity Assay, Luciferase, Stability Assay, Software